In vitro ADME testing services market is likely to be worth USD 2.2 billion by 2030>>>>>>

Roots Analysis has done a detailed study on ““In Vitro ADME Testing Services Market, 2019-2030” covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
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Key Market Insights 
  • Over 90 firms are actively involved in providing vitro ADME testing services; of these, over 30 players claim to have the capabilities to offer end-to-end services
  • Majority of the companies offer assays for drug metabolism and elimination testing for both small molecule and biologic drugs; followed by companies offering assays for absorption and distribution testing
  • Featuring the presence of small-mid sized firms, the in vitro ADME testing service provider landscape is well-distributed across various regions; these players have adopted various business models to cater to the evolving needs of the clients
  • Several players involved in this domain are steadily expanding their capabilities in order to enhance their respective in the in vitro ADME testing service portfolios and maintain a competitive edge in this industry
  • Various mergers and acquisitions have taken place from 2005-2018 between industry stakeholders in this domain, for addition of capabilities (primarily related to drug metabolism and pharmacokinetics testing) and geographical expansion / consolidation
  • Driven by the increasing demand for effective pharmacological interventions across a wide range of therapeutic areas, the market is expected to witness sustained growth in future
  • In the long-term, the projected opportunity is anticipated to be well distributed across various geographies, type of sponsors and type of services / assays
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Table of Contents
1.         PREFACE
1.1.       Scope of the Report
1.2.       Research Methodology
1.3.       Chapter Outlines
2.         EXECUTIVE SUMMARY
 
3.         INTRODUCTION
3.1.       Chapter Overview
3.2.       The Drug Discovery and Development Process
3.3.       Introduction to Absorption, Distribution, Metabolism and Excretion (ADME) Testing
3.3.1.    Absorption
3.3.2.    Distribution
3.3.3.    Metabolism
3.3.4.    Excretion
3.4.       Importance of ADME Studies in Early Stage Research
3.5.       Types of ADME Studies in Discovery and Preclinical Development
3.6.       Types of Assays Used in ADME Testing
3.7.       Types of ADME Testing Studies
3.7.1.    In Vitro ADME Testing Studies
3.7.2.    In Silico ADME Testing Studies
3.7.3.    In Vivo ADME Testing Studies
3.8.       Key Drivers for ADME Testing Studies
3.9.       Concluding Remarks
4.         GUDE TO OUTSOURCING
4.1.       Chapter Overview
4.2.       Outsourcing ADME Testing Services
4.3.       Guiding Models for Outsourcing
4.3.1.    Transactional Outsourcing Model
4.3.2.    Performance-based Outsourcing Model
4.3.3.    Outcomes-based Outsourcing Model
4.3.4.    Phase-dependent Outsourcing Model
4.4.       Selecting a Contract Research Organization (CRO) Partner
4.4.1.    Key Considerations
4.5.       Role of CROs in Drug Development
4.5.1.    Discovery and Preclinical Research
4.5.2.    Early Clinical Research
4.5.3.    Late Stage Clinical Research
4.6.       Benefits of Outsourcing ADME Testing Services
4.7.       Risks and Challenges Associated with Outsourcing ADME Testing Services
4.8.       Concluding Remarks
5.         MARKET LANDSCAPE
5.1.       Chapter Overview
5.1.       Chapter Overview
5.2.       In Vitro ADME Testing Services: List of Industry Players
5.2.1.    Analysis by Year of Establishment
5.2.2.    Analysis by Geographical Location
5.2.3.    Analysis by Company Size
5.2.4.    Analysis by Type of Service Offering
5.2.5.    Analysis by Type of In Vitro ADME Assays
5.2.6.    Analysis by Type of Molecule
5.2.7.    Analysis by Type of Clientele
5.2.8.    Logo Landscape: Distribution by Company Size and Location of Headquarters
5.3.       In Silico ADME Testing Services: List of Industry Players
6.         COMPANY PROFILES
6.1.       Chapter Overview
6.2.       Key Players based in North America
6.2.1.    Albany Molecular Research (AMRI)
6.2.1.1. Company Snapshot
6.2.1.2. Financial Information
6.2.1.3. ADME Testing Specific Service Portfolio
6.2.1.4. Recent Developments and Future Outlook
6.2.2.    Charles River Laboratories
6.2.2.1. Company Snapshot
6.2.2.2. Financial Information
6.2.2.3. ADME Testing Specific Service Portfolio
6.2.2.4. Recent Developments and Future Outlook
6.2.3.    Pharmaceutical Product Development (PPD)
6.2.3.1. Company Snapshot
6.2.3.2. ADME Testing Specific Service Portfolio
6.2.3.3. Recent Developments and Future Outlook
6.2.4.    RTI International
6.2.4.1. Company Snapshot
6.2.4.2. Financial Information
6.2.4.3. ADME Testing Specific Service Portfolio
6.2.4.4. Recent Developments and Future Outlook
6.3.       Key Players based in Europe
6.3.1.    Eurofins Scientific
6.3.1.1. Company Snapshot
6.3.1.2. Financial Information
6.3.1.3. ADME Testing Specific Service Portfolio
6.3.1.4. Recent Developments and Future Outlook
6.3.2.    Evotec
6.3.2.1. Company Snapshot
6.3.2.2. Financial Information
6.3.2.3. ADME Testing Specific Service Portfolio
6.3.2.4. Recent Developments and Future Outlook
6.3.3.    Galapagos
6.3.3.1. Company Snapshot
6.3.3.2. Financial Information
6.3.3.3. ADME Testing Specific Service Portfolio
6.3.3.4. Recent Developments and Future Outlook
6.3.4.    Tecan Group
6.3.4.1. Company Snapshot
6.3.4.2. Financial Information
6.3.4.3. ADME Testing Specific Service Portfolio
6.3.4.4. Recent Developments and Future Outlook
6.4.       Key Players based in Asia-Pacific
6.4.1.    GVK Biosciences
6.4.1.1. Company Snapshot
6.4.1.2. ADME Testing Specific Service Portfolio
6.4.1.3. Recent Developments and Future Outlook
6.4.2.    Pharmaron
6.4.2.1. Company Snapshot
6.4.2.2. ADME Testing Specific Service Portfolio
6.4.2.3. Recent Developments and Future Outlook
6.4.3.    Sai Life Sciences
6.4.3.1. Company Snapshot
6.4.3.2. ADME Testing Specific Service Portfolio
6.4.3.3. Recent Developments and Future Outlook
6.4.4.    Shanghai Medicilon
6.4.4.1. Company Snapshot
6.4.4.2. ADME Testing Specific Service Portfolio
6.4.4.3. Recent Developments and Future Outlook
6.4.5.    Syngene International
6.4.5.1. Company Snapshot
6.4.5.2. Financial Information
6.4.5.3. ADME Testing Specific Service Portfolio
6.4.5.4. Recent Developments and Future Outlook
6.4.6.    WuXi AppTec
6.4.6.1. Company Snapshot
6.4.6.2. Financial Information
6.4.6.3. ADME Testing Specific Service Portfolio
6.4.6.4. Recent Developments and Future Outlook
7.         BENCHMARK ANALYSIS
7.1.       Chapter Overview
7.2.       Benchmark Analysis: Methodology
7.3.       Benchmark Analysis: Peer Groups
7.3.1.    Peer Group I
7.3.2.    Peer Group II
7.3.3.    Peer Group III
7.3.4.    Peer Group IV
7.3.5.    Peer Group V
7.3.6.    Peer Group VI
7.3.7.    Peer Group VII
7.3.8.    Peer Group VIII
7.4.       Concluding Remarks
8.         MERGERS AND ACQUISITIONS
8.1.       Chapter Overview
8.2.       In Vitro ADME Testing Services: Mergers and Acquisitions
8.2.1.    Cumulative Year-wise Trend
8.2.2.    Geographical Activity
8.2.3.    Ownership Change Matrix
8.2.4.    Most Active Players: Analysis by Number of Acquisitions
8.2.5.    Key Value Drivers
8.2.6.    Key Acquisitions: Deal Multiples
9.         REGULATORY RECOMMENDATIONS AND GUIDELINES
9.1.       Chapter Overview
9.2.       Regulatory Guidelines Issued by International Regulatory Agencies
9.2.1.    The International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use
9.2.2.    World Health Organization (WHO)
9.2.3.    Organisation for Economic Co-operation and Development (OECD)
9.3.       Regulatory Guidelines Issued by Regional Regulatory Agencies
9.3.1.    United States Food and Drug Administration (USFDA), US
9.3.2.    European Medicine Agency (EMA), Europe
9.3.3.    Ministry of Health, Labour and Welfare (MHLW), Japan
9.4.       In Vitro ADME Testing Service Providers: Information on Regulatory Approval
10.        MARKET FORECAST
10.1.     Chapter Overview
10.2.     Forecast Methodology and Key Assumptions
10.3.     Overall In Vitro ADME Testing Services Market, 2019-2030
10.4.     In Vitro ADME Testing Services Market: Distribution by Regions, 2019-2030
10.4.1.  In Vitro ADME Testing Services Market in North America, 2019-2030
10.4.1.1. In Vitro ADME Testing Services Market in the US, 2019-2030
10.4.1.2. In Vitro ADME Testing Services Market in Canada, 2019-2030
10.4.2.  In Vitro ADME Testing Services Market in Europe, 2019-2030
10.4.2.1. In Vitro ADME Testing Services Market in Germany, 2019-2030
10.4.2.2. In Vitro ADME Testing Services Market in France, 2019-2030
10.4.2.3. In Vitro ADME Testing Services Market in the UK, 2019-2030
10.4.2.4. In Vitro ADME Testing Services Market in Italy, 2019-2030
10.4.2.5. In Vitro ADME Testing Services Market in Spain, 2019-2030
10.4.2.6. In Vitro ADME Testing Services Market in Rest of Europe, 2019-2030
10.4.3.  In Vitro ADME Testing Services Market in Asia-Pacific and Rest of the World, 2019-2030
10.4.3.1. In Vitro ADME Testing Services Market in Japan, 2019-2030
10.4.3.2. In Vitro ADME Testing Services Market in China, 2018-2028
10.4.3.3. In Vitro ADME Testing Services Market in India, 2019-2030
10.4.3.4. In Vitro ADME Testing Services Market in Rest of the World, 2019-2030
10.5.     In Vitro ADME Testing Services Market: Distribution by Type of Services, 2019-2030
10.5.1.  In Vitro ADME Testing Services Market for Absorption Testing, 2019-2030
10.5.2.  In Vitro ADME Testing Services Market for Distribution Testing, 2019-2030
10.5.3.  In Vitro ADME Testing Services Market for Metabolism and Elimination Testing, 2019-2030
10.6.     In Vitro ADME Testing Services Market: Distribution by Type of Assays, 2019-2030
10.6.1.  In Vitro ADME Testing Services Market for Caco-2 Permeability Assay, 2019-2030
10.6.2.  In Vitro ADME Testing Services Market for PAMPA Permeability Assay, 2019-2030
10.6.3.  In Vitro ADME Testing Services Market for MDCK Permeability Assay, 2019-2030
10.6.4.  In Vitro ADME Testing Services Market for Protein Binding Assay, 2019-2030
10.6.5.  In Vitro ADME Testing Services Market for Blood Brain Barrier Assay, 2019-2030
10.6.6.  In Vitro ADME Testing Services Market for Assays for Studying Blood to Plasma Ratio, 2019-2030
10.6.7.  In Vitro ADME Testing Services Market for Metabolic Stability / Clearance Assay, 2019-2030
10.6.8.  In Vitro ADME Testing Services Market for Enzyme Induction Assay, 2019-2030
10.6.9.  In Vitro ADME Testing Services Market for Enzyme Inhibition Assay, 2019-2030
10.6.10. In Vitro ADME Testing Services Market for Metabolite Profiling and Screening / Identification Assay, 2019-2030
10.6.11. In Vitro ADME Testing Services Market for Metabolite Production Assay, 2019-2030
10.6.12. In Vitro ADME Testing Services Market for Reaction Phenotyping Assay, 2019-2030
10.6.13. In Vitro ADME Testing Services Market for Transporter Interactions Assay, 2019-2030
10.7.     In Vitro ADME Testing Services Market: Distribution by Type of Molecules, 2019-2030
10.7.1.  In Vitro ADME Testing Services Market for Small Molecules, 2019-2030
10.7.2.  In Vitro ADME Testing Services Market for Biologics, 2019-2030
10.8.     In Vitro ADME Testing Services Market: Distribution by Therapeutic Areas, 2019-2030
10.8.1.  In Vitro ADME Testing Services Market for Blood Disorders, 2019-2030
10.8.2.  In Vitro ADME Testing Services Market for Cardiovascular Disorders, 2019-2030
10.8.3.  In Vitro ADME Testing Services Market for Gastrointestinal and Digestive Disorders, 2019-2030
10.8.4.  In Vitro ADME Testing Services Market for Hormonal Disorders, 2019-2030
10.8.5.  In Vitro ADME Testing Services Market for Infectious Diseases, 2019-2030
10.8.6.  In Vitro ADME Testing Services Market for Immunological Disorders, 2019-2030
10.8.7.  In Vitro ADME Testing Services Market for Mental Disorders, 2019-2030
10.8.8.  In Vitro ADME Testing Services Market for Metabolic Disorders, 2019-2030
10.8.9.  In Vitro ADME Testing Services Market for Neurological Disorders, 2019-2030
10.8.10. In Vitro ADME Testing Services Market for Cancers, 2019-2030
10.8.11. In Vitro ADME Testing Services Market for Respiratory Disorders, 2019-2030
10.8.12. In Vitro ADME Testing Services Market for Skin Disorders, 2019-2030
10.8.13. In Vitro ADME Testing Services Market for Urogenital Disorders, 2019-2030
10.8.14. In Vitro ADME Testing Services Market for Other Disorders, 2019-2030
10.8.15. In Vitro ADME Testing Services Market: Market Attractiveness Analysis by Therapeutic Areas, 2019-2030
10.9.     In Vitro ADME Testing Services Market: Distribution by Type of Sponsors, 2019-2030
10.9.1.  In Vitro ADME Testing Services Market for Industry Players, 2019-2030
10.9.2.  In Vitro ADME Testing Services Market for Non-Industry Players, 2019-2030
11.        CONCLUSION
11.1.     Conducting In Vitro ADME Studies During the Early Stages of Drug Development has Demonstrated the Potential to Improve the Probability of Clinical Success
11.2.     The Contract Services Landscape Features Several Capable CROs Offering Services for In Vitro ADME Testing; Most of these Companies are based in North America and Europe
11.3.     Current Market Leaders Have Vast In Vitro ADME Testing Service Portfolios, Drug Metabolism-related Assays Represent the Major Fraction
11.4.     Stakeholders are Actively Expanding their Existing Capabilities to Cater to the Increasing Demand; this is Evident in the Number of Acquisitions Reported over the Past Decade
11.5.     Driven by the Need to Optimize the Drug Discovery and Development Process, the In Vitro ADME Testing Services Market is Expected to Grow at a Healthy Pace in the Foreseen Future
12.        EXECUTIVE INSIGHTS
12.1.     Chapter Overview
12.2.     490 BioTech
12.2.1.  Company Snapshot
12.2.2.  Interview Transcript: Dan Close, Chief Scientific Officer
12.3.     JRF Global
12.3.1.  Company Snapshot
12.3.2.  Interview Transcript: Sridhar Iyer, Director and Global Head, Business Development and Sarang Gorte, Assistant Manager, Business Development
13.        APPENDIX I: TABULATED DATA
 
14.        APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS
 
Contact Details
Gaurav Chaudhary
+1 (415) 800 3415
[email protected]

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